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Automatic Vial Filling and Capping Machine

short description:

Vial Liquid Filling and Stoppering Machine is suitable for the liquid filling and rubber stoppering of glass vials. Machine complete in pleasing matt finished stainless steel construction. The basic unit consists of turntable/unscrambler, SS Stat conveyor belt, Highly efficient and precision built S.S. 316 Syringes, non- toxic synthetic rubber tubing and easy reach compact panel.

The minimal distance between filling and stoppering units reduces the risk of contamination.  The machines are designed for operation in a sterile area and for use under laminar flow protection.  The un-scrambler itself has been redesigned to eliminate dead ends and difficult-to-clean spots.

 


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vial filling (1)
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vial filling (2)

Overview

The vial filling production line is composed of ultrasonic bottle washing machine, dryer sterilizer, filling stoppering machine, and capping machine. It can complete spraying water, ultrasonic cleaning, flushing of inner and outer wall of bottle, preheating, drying and sterilization, heat source removing, cooling, bottle unscrambling, (nitrogen pre-filling), filling, (nitrogen post-filling), stopper unscrambling, stopper pressing, cap unscrambling, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately, or in linkage line. The whole line is mainly used for filling of vial liquid injections and freeze-dried powder injections in pharmaceutical factories, it can also be applied to production of antibiotics, bio-pharmaceuticals, chemical pharmaceuticals, blood products etc.

Parameter

 

Model SHPD4 SHPD6 SHPD8 SHPD10 SHPD12 SHPD20 SHPD24
Applicable specifications 2~30ml vial bottles
Filling heads 4 6 8 10 12 20 24
Production capacity 50-100bts/min 80-150bts/min 100-200bts/min 150-300bts/min 200-400bts/min 250-500bts/min 300-600bts/min
Stoppling qualification rate >=99%
Laminar air cleanliness 100 grade
Vacuum pumping speed 10m3/h 30m3/h 50m3/h 60m3/h 60m3/h 100m3/h 120m3/h
Power consumption 5kw
Power supply 220V/380V 50Hz

Machine configuration

Frame

SUS304 Stainless steel

Parts in contact with liquid

SUS316L Stainless steel

Electrical parts

 图片1

Pneumatic part

 图片2

Features

1.The vial filling sealing production line meets new GMP requirements, and the cleaning effect meets the new Pharmacopoeia standards and requirements.
2.The whole line can adopt straight-line layout or wall-to-wall L-shaped layout to reduce risk of cross-contamination and ensure aseptic level.
3.Applicable specification: 1ml-100ml vial (as per user's requirement)
4.Production Capacity: 1000-36000BPH
5.Number of filling head: 1-20, to be selected according to the output
6.Filling Accuracy of vial filling machine: ≤ ±1% (according to drug characteristics)
7.Choice of various filling pumps: glass pump, metal pump, peristaltic pump, ceramic pump;
8.Capping qualified rate: ≥99.9%
9.Compact and simple structure, occupies less area;
10.Stable product performance, easy and reliable operation, beautiful appearance;
11.High degree of automation, few operators required;

Working Process

The incoming dry vial (sterilized and siliconised) are fed through the unscrambler and suitably guided on the moving delrin slat conveyor belt at the required speed of the correct placement below filling unit. The filling unit consists of Filling Head, Syringes & Nozzles which are used for liquid filling. The syringes are made of S.S. 316 construction and both, glass as well as S.S. syringes can be used. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided.

The Machine Details

1)This is filling pipes, it is high quality imported pipes.There are the valves on the pipe, it will suck liquid back after once filling. So filling nozzles will not leakage. 

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2) The multi roller structure of our peristaltic pump further improves the stability and non impact of filling and makes the liquid filling stable and not easy to blister. It is especially suitable for filling the liquid with high requirement.

3)This is aluminum Cap sealing head. It has three sealing roller. It will sealing Cap from four sides, so the sealed Cap is very tighten and beautiful. It will not damage Cap or leakage Cap.

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